It is uncertain whether other adverse effects, rather than N/V, may have arisen from cannabinoid administration. Cannabis is the most commonly used illicit drug in the USA.12 Although it has documented medicinal benefits as an antiemetic, chronic cannabis use has recently been linked to CHS. The exact pathophysiology of this phenomenon remains undetermined, but few theories exist in the medical literature. The duration of cannabis administration ranged between 6 months to 11 years may precipitate symptoms of CHS. The Rome IV diagnostic criteria of CHS require cannabinoid use and persistence of N/V symptoms for at least the past 6 months.
- These therapies may offer transient relief but are not comprehensive solutions for CHS symptomatology.
- The patient’s condition had improved at 7-month follow-up, and she declined surgical consultation.
- Importantly, for the definition of cyclic vomiting syndrome, these episodes of vomiting cannot be attributed to other disorders.
- Chronic cannabinoid usage can lead to recurrent N/V with distinct pathogenesis, known as CHS.
Topical Capsaicin
This increased blood flow to the skin and peripheral tissues may help shift blood volume away from the gastrointestinal tract, potentially alleviating nausea and vomiting symptoms by reducing visceral hypersensitivity and enhancing overall comfort levels. Health care provider and clinician education, such as this activity, as crucial to the advancement of care in this condition because it is not usually at the top of the differential list because of the https://ecosoberhouse.com/ lack of research and familiarity in the healthcare community. The same factors apply to clinicians, specialists, nurses, and pharmacists, as well as other healthcare personnel, to consider the diagnosis in any chronic vomiting disorder, and to better inform themselves regarding the condition. They should also have the freedom and empowerment to speak up to other team members if they feel that this may be getting overlooked in the diagnostic picture. Since the only treatment is the removal of the offending agent, accurate diagnosis is the only portal to actual management.
Unveiling Treatment Strategies for Cannabis Hyperemesis Syndrome (CHS)
One 2018 study found that 32.9% of self-reported frequent marijuana users who’d gone to the emergency room (ER) had symptoms of CHS. And a 2022 Canadian study found that ER visits for CHS-related problems had increased 13-fold between 2014 and 2021. (Recreational use and sale of cannabis in Canada was legalized starting in 2018).
Is there any scientific research about CHS at all?
Furthermore, heat-induced vasodilation might facilitate toxin elimination through the skin, aiding in the detoxification process and potentially contributing to symptom improvement in individuals with CHS. The treatment of CHS requires completely stopping the use of marijuana. If you’re struggling or reluctant to do this simple and effective test, it strongly suggests that you are dealing with the very real and valid effects of dependence.
TRPV1 Receptor Stimulation
Despite the appropriate statistical methods used in the study cannabinoid hyperemesis syndrome conducted by Wagner et al. 24, the subgroup analysis presented a serious risk of bias due to a small sample that may contain unbalanced prognostic factors. The retrospective cohort conducted by Yusuf et al. 25 had a moderate bias in selecting patients in the ED, as there was selective reporting of patient outcomes, as only the LOS in the ED was measured. While conventional antiemetic medications like serotonin 5-HT3 receptor antagonists and dopamine antagonists can be prescribed to manage nausea and vomiting in CHS patients, their efficacy in CHS cases is limited. These therapies may offer transient relief but are not comprehensive solutions for CHS symptomatology.
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